ParaView

ParaView is an open-source, multi-platform data analysis and visualization application. ParaView users can quickly build visualizations to analyze their data using qualitative and quantitative techniques. The data exploration can be done interactively in 3D or programmatically using ParaView’s batch processing capabilities. ParaView was developed to analyze extremely large datasets using distributed memory computing resources. It can be run on supercomputers to analyze datasets of petascale as well as on laptops for smaller data. ParaView is an application framework as well as a turn-key application.

The ParaView code base is designed in such a way that all of its components can be reused to quickly develop vertical applications. This flexibility allows ParaView developers to quickly develop applications that have specific functionality for a specific problem domain. ParaView runs on distributed and shared memory parallel and single processor systems. It has been successfully deployed on Windows, Mac OS X, Linux, SGI, IBM Blue Gene, Cray and various Unix workstations, clusters and supercomputers. Under the hood, ParaView uses the Visualization Toolkit (VTK) as the data processing and rendering engine and has a user interface written using Qt® The goals of the ParaView team include the following:

Develop an open-source, multi-platform visualization application.
Support distributed computation models to process large data sets.
Create an open, flexible, and intuitive user interface.
Develop an extensible architecture based on open standards.

Other software

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3D Slicer

3D Slicer is: A software platform for the analysis (including registration and interactive segmentation) and visualization (including volume rendering) of medical images and for research in image guided therapy. A free, open source software available on multiple operating systems: Linux, MacOSX and Windows Extensible, with powerful plug-in capabilities for adding algorithms and applications. Features include: Multi organ: from head to toe. Support for multi-modality imaging including, MRI, CT, US, nuclear medicine, and microscopy. Bidirectional interface for devices. There is no restriction on use, but Slicer is not approved for clinical use and intended for research. Permissions and compliance with applicable rules are the responsibility of the user.

Data analysis and visualisation

3DSpineS

Dendritic spines of pyramidal neurons are the targets of most excitatory synapses in the cerebral cortex and their morphology appears to be critical from the functional point of view. Thus, characterizing this morphology is necessary to link structural and functional spine data and thus interpret and make them more meaningful. We have used a large database of more than 7,000 individually 3D reconstructed dendritic spines from human cortical pyramidal neurons that is first transformed into a set of 54 quantitative features characterizing spine geometry mathematically. The resulting data set is grouped into spine clusters based on a probabilistic model with Gaussian finite mixtures. We uncover six groups of spines whose discriminative characteristics are identified with machine learning methods as a set of rules. The clustering model allows us to simulate accurate spines from human pyramidal neurons to suggest new hypotheses of the functional organization of these cells.

Data analysis and visualisationData

3D Structure Tensor Analysis

A Structure Tensor Analysis (STA) tool for the characterization of local 3D orientation in TIFF image stacks. This tool is based on the evaluation of local image intensity gradients. In addition to the local 3D orientation, it also provides a full analysis of local gradient strength, structure disarray, shape and fractional anisotropy indices.

Data analysis and visualisation

Other software

3D Slicer

3DSpineS

3D Structure Tensor Analysis

Make the most out of EBRAINS